Guitars in Parallel
Send a guitar through a parallel bus and put a noise gate followed by effects on the bus.
Why? If you set it up properly, you can have the sound change based on the input volume, e.g. pick the strings harder and it will bring in the effects, play quieter and leave the tone clean. Depending on how the noise gate is set, you can have this fading in and out or cutting in and out, almost stuttering. This is a more drastic change than what you'd get out of a valve amp set just on the edge.
Steps
Variations
I've attached a sample and a screenshot [0] of how it works in Logic Pro. I actually used a few more effects than just a distortion to make it work better for me.
Try it and let me know how you get on.
Part of a series [0] by Award Sounds [1] offering a selection of creative ideas to kick-start or rejuvenate a composition.